Rozlytrek (Entrectinib)
- Medicine Name: Rozlytrek
- Generic Name: Entrectinib
- Dosage Form & Strength: Capsules: 100 mg and 200 mg
- Manufactured By: Genentech, Inc.
Medical Uses
Rozlytrek is a kinase inhibitor used for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are ROS1-positive.
Rozlytrek is also used for adult and pediatric patients aged 12 years and older with NTRK fusion-positive solid tumors.
Recommended Dosage: The recommended dosage for ROS1-Positive Non-Small Cell Lung Cancer is 600 mg orally once daily with or without food until disease progression or unacceptable toxicity.
The recommended dosage for NTRK Gene Fusion-Positive Solid Tumors in adults is 600 mg orally once daily, and for Pediatric Patients aged 12 years and older (Adolescents) with Body Surface Area (BSA) greater than 1.50 m2 dose is 600 mg; for BSA 1.11 to 1.50 m2 dose is 500 mg and for BSA 0.91 to 1.10 m2 dose is 400 mg. Take this medicine orally once daily with or without food until the disease is progressive or unacceptable toxicity occurs.
Warning & Precautions
- Congestive heart failure (CHF) may occur. Assess left ventricular ejection fraction (LVEF) before initiating treatment with entrectinib 100 mg capsule or any other dosage strength in patients with symptoms or known risk factors for CHF.
- Monitor patients for clinical signs/symptoms of CHF, including edema and shortness of breath. For patients with myocarditis, with or without a reduced ejection fraction, MRI or cardiac biopsy may be needed to make the diagnosis.
- A broad spectrum of CNS adverse reactions may occur in patients with rozlytrek 100 mg capsule, including mood disorders, cognitive impairment, dizziness, and sleep disturbances. Patients should not drive or operate hazardous machinery in case they are experiencing CNS adverse reactions.
- Entrectinib increases the probability of fractures. Promptly assess patients with signs/symptoms (e.g., changes in mobility, pain, deformity) of fractures. There are no findings on the effects of the entrectinib capsule on the healing of known fractures and the probability of future fractures.
- Increased AST of any grade may occur. Monitor liver tests, including AST and ALT, every 14 days during the initial month of treatment, then monthly after that. Withhold or permanently discontinue Entrectinib therapy on behalf of the severity. If withheld, resume therapy with Entrectinib at the same or reduced dose.
- Patients may experience hyperuricemia. Assess serum uric acid levels before initiating treatment with Rozlytrek capsule and periodically during treatment. Also, monitor patients for signs and symptoms of hyperuricemia. Start treatment with urate-lowering drugs and withhold Rozlytrek for signs/symptoms of hyperuricemia.
- Findings and its mechanism of action suggest that Entrectinib can cause fetal harm if administered to a pregnant woman. Also, mothers should avoid breastfeeding during treatment with Entrectinib and for 7 days after the final dose.
Documentation & Availability
What documents are required to import ROZLYTREK to India?
ROZLYTREK capsules can be imported by patients or government hospitals only in the name of the patients.
The following documentation are needed to import the product:
- A valid prescription from a qualified doctor.
- Patient’s diagnostic reports.
- Patient’s ID proof (issued by the Government of India).
How is the order confirmed?
The order will be confirmed only after the receipt of:
- A valid prescription from a doctor.
- Import permit if applicable.
Is ROZLYTREK available in India?
ROZLYTREK is a (prescription drug, prescription medication or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.
S S Healthcare (S S Healthcare) helps import cancer medicines on the named patient supply (NPS). S S Healthcare is the facilitator providing input
- On availability in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc.)
- Medicine Price.
- Finding Genuine and reliable sources from Canada, Europe, the USA and Australia
- Ensuring 100% transparency.
ROZLYTREK can be made available to patients, doctors and hospitals in Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow and Pune and other cities in India. The order will be confirmed only after receiving a valid prescription from the doctor and import permit.
S S Healthcare (S S Healthcare) can facilitate the supply of ROZLYTREK (prescription medicines) to all locations in the world and India after fulfilling the legal requirement (if applicable)
Please contact +91-7575883015 | Toll-Free No: +91-7575883015 or write us at sshealthcare1012@gmail.com for Entrectinib price in India.
We guarantee quality and delivery anywhere in the world as per the buyer’s requirements.
Sourcing & Delivery
S S Healthcare can source the ROZLYTREK (Cancer Treatment Medicines) from across the globe and can supply. S S Healthcare offers its customers worldwide access to the best available treatment.
S S Healthcare can dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.
FAQ
What is the Generic Name for the trade name drug Rozlytrek®?
Rozlytrek is the trade name for the drug Entrectinib.
Does the FDA approve Rozlytrek®?
Yes, Rozlytrek® is approved by the FDA. Date of approval: August 15, 2019.
What is Rozlytrek®?
Rozlytrek is a prescription medication and is used to treat:
- adult patients with ROS1+ metastatic non-small lung cancer
- adults and children aged 12 years and older with NTRK fusion-positive solid tumors.
What is the dosage and form of Rozlytrek® supplied?
This medicinal product is typically supplied in 2 dosage strengths, which are as follows:
- Rozlytrek 100 mg capsule
- Rozlytrek 200 mg capsule
What are the ingredients of the medicine Rozlytrek?
The active ingredient in the medicine Rozlytrek is Entrectinib, with inactive ingredients tartaric acid, lactose anhydrous, hypromellose, crospovidone, microcrystalline cellulose, colloidal silicon dioxide, and magnesium stearate.
What are the most common side effects due to Rozlytrek®?
The most common side effects due to Rozlytrek® include nausea, fatigue, cognitive impairment, constipation, dysgeusia, edema, dizziness, diarrhea, dysesthesia, dyspnea, myalgia, and increased weight, cough, vomiting, pyrexia, vision disorders, and arthralgia.
How much does Rozlytrek® cost in India?
The Rozlytrek cost in India is reasonable. To authenticate this NSCLC medication, you can call or WhatsApp +91-7575883015 or send mail to sshealthcare1012@gmail.com.
What are the storage conditions of Rozlytrek®?
Store the capsules of Rozlytrek at a temperature below 86°F (30°C).
Is it safe to buy Rozlytrek® online?
Yes, it is safe to buy this drug online. If you want to buy Rozlytrek capsule online, always look for an authentic, legitimate, WHO-GDP and ISO-certified Pharmaceutical Wholesaler/Distributor/Supplier.
What are the Highlights of prescribing information for Rozlytrek®?
Click Here to download full Rozlytrek prescribing information.
Contact Patient Support
If you have any questions or need any help, contact our Patient Support Team. We will get in touch with you within 24 hours from Monday to Friday between 9:00 and 10:00 CET.
Email Address
Sshealthcare1012@gmail.com
+91 7575883015
Landline
079 48916267
Disclaimer
All Trademarks and Brands that appear on the website belong to their respective owners, and S S Healthcare does not lay any claim on them. We only provide information.
