Ayvakit (Avapritinib)
- Medicine Name: Ayvakit
- Generic Name: Avapritinib
- Dosage Form & Strength: Tablets: 25 mg, 50 mg, 100 mg, 200 mg and 300 mg
- Manufactured By: Blueprint Medicines Corporation
Medical Uses
Ayvakit is a kinase inhibitor used for: Gastrointestinal Stromal Tumor (GIST): to treat adults with unresectable or metastatic GIST harboring a platelet-derived growth factor receptor alpha (PDGFRA) exon 18 mutation, including PDGFRA D842V mutations.
Advanced Systemic Mastocytosis (AdvSM): to treat adult patients with AdvSM. Advanced Systemic Mastocytosis includes patients with mast cell leukemia, aggressive systemic mastocytosis, systemic mastocytosis with an associated hematological neoplasm (SM-AHN).
Recommended Dosage: The recommended dosage is 300 mg orally once daily in patients with GIST. Continue treatment until the disease is progressive or unacceptable toxicity occurs.
The recommended dosage is ayvakit 200 mg orally once daily in patients with AdvSM. Continue treatment with Ayvakit until the disease is progressive or unacceptable toxicity occurs.
Administer the tablets of Ayvakit orally on an empty stomach, at least 60 minutes before or 120 minutes after a meal. Avoid making up for a missed ayvakit dose within eight hours of the next scheduled dose. Do not repeat the dose in case vomiting occurs after taking Ayvakit dose but continue with the next scheduled dose.
Warning & Precautions
- Severe intracranial hemorrhage may occur with avapritinib 300 mg treatment. Assess patients closely for the risk of intracranial hemorrhage including those with vascular aneurysm, thrombocytopenia or a history of intracranial hemorrhage or cerebrovascular accident within the earlier year.
- In patients with AdvSM, perform platelet count prior to initiating therapy; avapritinib 50 mg or any other dosage strength is not recommended in patients with Advanced Systemic Mastocytosis with platelet counts < 50 X 109.
- Cognitive adverse events can appear in patients receiving avapritinib 25 mg tablets. On behalf of the severity, withhold avapritinib and then resume at the same dose or at a decreased dose upon improvement, or permanently discontinue avapritinib.
- Avapritinib can cause fetal harm if administered to pregnant women. Males and females of reproductive potential should use effective contraception during treatment with avapritinib 200 mg and for 6 weeks following the final dose.
- Respective women should not breastfeed during treatment with tablets of Avapritinib and for 2 weeks following the last dose.
Documentation & Availability
What documents are required to import AYVAKIT to India?
AYVAKIT (avapritinib) tablets can be imported by patients or government hospitals on the name of the patients only.
The following documentation are needed to import the product:
- A valid prescription from a qualified doctor.
- Patient’s diagnostic reports.
- Patient’s ID proof (issued by the Government of India).
How is the order confirmed?
The order will be confirmed only after the receipt of:
- A valid prescription from a doctor.
- Import permit if applicable.
Is AYVAKIT available in India?
AYVAKIT (avapritinib tablets) is a (prescription drug, prescription medication or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.
S S Healthcare (S S Healthcare) helps import cancer medicines on the named patient supply (NPS). S S Healthcare is facilitator providing input
- On availability in India (Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc.)
- Medicine Price.
- Finding Genuine and reliable source from Canada, Europe, USA and Australia
- Ensuring 100% transparency.
AYVAKIT can be made available to patients, doctors and hospitals at Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and import permit.
S S Healthcare (S S Healthcare) can facilitate the supply of AYVAKIT (prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable)
Please contact +91-7575883015 | Toll-Free No: +91-7575883015 or write us at sshealthcare1012@gmail.com for avapritinib tablet price in India.
We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.
Sourcing & Delivery
S S Healthcare is able to source the AYVAKIT (Cancer Treatment Medicines) from across the globe, and has the ability to supply. S S Healthcare offers its customers worldwide access to the best available treatment.
S S Healthcare is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.
FAQ
What is the Generic Name for the trade name drug Ayvakit®?
Avapritinib is Generic Name for the trade name drug Ayvakit®.
What is the Manufacturer Name of Ayvakit®?
Ayvakit® is manufactured by Blueprint Medicines Corporation.
Is Ayvakit® approved by the FDA?
Yes, Ayvakit® is approved by the FDA. Date of approval: January 9, 2020.
What is Ayvakit®?
Ayvakit (avapritinib) is a prescription medication aimed to treat adults with:
- gastrointestinal stromal tumor (GIST)
- advanced systemic mastocytosis (AdvSM)
What is the dosage and form of Ayvakit® supplied?
Ayvakit® is supplied as Tablets: 25 mg, 50 mg, 100 mg, 200 mg and 300 mg for oral administration.
What are the most common side effects due to Ayvakit®?
Most common side effects due to Ayvakit® include: GIST: cognitive impairment, edema, nausea, fatigue/asthenia, vomiting, diarrhea, decreased appetite, abdominal pain, hair color changes, increased lacrimation, constipation, rash, and dizziness.
AdvSM: diarrhea, nausea, edema, and fatigue/asthenia.
How much does Ayvakit® cost in India?
The Ayvakit cost in India can be reasonable. In order to procure this medication for GIST authentically, you can call or WhatsApp +91-7575883015 or send mail to sshealthcare1012@gmail.com.
What are the storage conditions of Ayvakit®?
Store the tablets of Ayvakit at temperature 20°C to 25°C (68°F to 77°F); excursions are permitted from 15°C to 30°C (59°F to 86°F).
What are the Highlights of prescribing information for Ayvakit®?
Click Here to download full Ayvakit prescribing information.
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