Ipilimumab Injection 50mg and 200 mg vial
- Name: Yervoy
- Generic Name: Ipilimumab
- Strength: Single use-vial
- Manufactured: Bristol-Myers Squibb Company
Medical Uses
- Ipilimumab was approved by the US Food and Drug Administration in the year of 2011 for treating patients with late-stage Melanoma that has spread or can not be removed by the surgery. It is a type of deadly skin cancer.
- Later, it was approved for the stage 3 patients as adjuvant therapy.
- On February 1, 2012, Ipilimumab was approved by Health Canada for the treatment of unresectable or metastatic melanoma in those patients who have failed or do not tolerate other systemic therapy for advanced disease.
- In November 2012, Ipilimumab was approved in the European Union, for the treatment of second line metastatic melanoma.
- The drug is undergoing clinical trials for the treatment of NSCLC, small cell lung cancer and metastatic hormone-refractory prostate cancer and bladder cancer.
- Ipilimumab is the active ingredient of Yervoy.
- It is unspecified if this drug is safe as well as effective in children who are less than 18 years of age.
- It is given to the patient into their vein through an IV line over 90 minutes.
- Yervoy FDA label should be stored under refrigeration at 2°C to 8°C (36°F to 46°F). Never freeze it. Vials should be protected from light.
What is Ipilimumab?
Ipilimumab is the generic name for the trade drug name Yervoy®. In some cases, health care professionals may use the generic name ipilimumab when referring to the trade drug name Yervoy.
Ipilimumab Injection Indication: Ipilimumab is a prescription medicine used to treat a kind of skin cancer called melanoma. It can be used:
- when your skin cancer melanoma has spread or not able to be removed by the surgery.
- In order to help prevent melanoma from coming back after it and lymph nodes that contain cancer have been removed by surgery.
Yervoy Side Effects: The most common side effects of Yervoy are fatigue, pruritus, rash, diarrhea and colitis. Some other common side effects at the 10 mg/kg dose may include vomiting, nausea, weight loss, headache, decreased appetite, pyrexia and insomnia.
What is Metastatic Melanoma?
Melanoma, also can be addressed as malignant melanoma. It is a type of skin cancer that begins from the pigment-producing cells called Melanocytes. Melanomas typically occur in the skin but can rarely occur in the mouth, intestines or eye. In females, it most commonly occurs on the legs, while in males it most commonly occurs on the back. Approximately 25% of melanomas begins from moles. Changement in the mole that may indicate melanoma include an increment in the size, irregular edges, skin breakdown, change in color and itchiness.
Can metastatic melanoma cancer be cured?
Early-stage melanomas can often be treated with the surgery alone, but more advanced melanoma cancers may require some other treatments. Sometimes it could be more than one type of treatment.
Based on the stage of the melanoma cancer and several other factors, your treatment might be as follows:Based on the stage of the melanoma cancer and several other factors, your treatment might be as follows:
- Surgery for Melanoma Skin Cancer
- Immunotherapy for Melanoma Skin Cancer
- Targeted Therapy Drugs for Melanoma Skin Cancer
- Chemotherapy for Melanoma Skin Cancer
- Radiation Therapy for Melanoma Skin Cancer
What Stage is Metastatic Melanoma?
Stage 4 melanoma also can be specified as metastatic melanoma; it means the cancerous cells start spreading beyond the skin and regional lymph nodes to the distant organs such as the lungs, liver or brain. In this stage cancer also has spread to the distant lymph nodes and also areas of the skin.
What is the best treatment for Metastatic Melanoma?
In order to treat advanced stage Melanoma, Ipilimumab is quite popular amongst healthcare providers. The drug is effective in deadly skin cancer treatment (Melanoma).
Does Yervoy Work for Skin Cancer?
CTLs (Cytotoxic T lymphocytes) can recognize and destroy the cancerous cells. However, an inhibitory mechanism resists and interrupts this destruction. Ipilimumab turns off this inhibitory mechanism and helps in boosting the body’s immune response against the cancerous cells.
What is the generic name of Yervoy ?
The generic name of Yervoy is Ipilimumab.
Who is the manufacturer of Yervoy?
Ipilimumab is manufactured by Bristol-Myers Squibb Company
Is Yervoy approved by USA FDA?
Yes, Ipilimumab is approved by FDA. The date of Approval is March’2011
Is Yervoy approved by European Authorities?
Yes, Ipilimumab is approved in most the countries in Europe.
What is the dosage form of Yervoy?
Ipilimumab is available as 50 mg vial (5 mg/mL) and 200 mg vial (5 mg/mL) Single use-vial
About Medicine.
Yervoy – Ipilimumab 50 mg and 200 mg. is supplied for Tenders, Emergency imports, Orphan drug, Reference listed drugs, Comparator Drug, Name patient medicine and Innovator samples etc.
How does yervoy work?
Ipilimumab works by attaching itself to normal T-cells. T-cells are part of the immune system. They fight infection and diseases. In some people T-cells can recognise and destroy melanoma cells. But a protein on the surface of T-cells, called CTLA-4, stops this happening. Ipilimumab blocks the protein so the T-cells can destroy melanoma cells.
What is Ipilimumab used for:
Yervoy (ipilimumab) is a monoclonal antibody used to treat late-stage, metastatic melanoma, a deadly skin cancer. Yervoy is thought to work by allowing the body’s immune system to recognize, target, and attack cells in these tumors.
How can I get Yervoy (Ipilimumab) in India?
Ipilimumab is not available or approved by drug authorities in India. However patients can access the product by getting import permission from government of India*
What is price of one vial of Ipilimumab?
You can call /at WhatsApp +91-7575883015 | Toll Free 1800 889 1064 or send mail to info@indianpharmanetwork.com know the cost /price.
Documentation & Availability
Is there any generic or bio similar available for Yervoy (Ipilimumab 50 mg and 200 mg).
There is no generic or bio similar available for Yervoy (Ipilimumab 50 mg and 200 mg) anywhere in the world.
What is price of one vial of Yervoy (Ipilimumab 50 mg and 200 mg)?
You can call /at whats app +91-7575883015 or send mail to info@indianpharmanetwork.com know the price.
Is it safe to buy Yervoy (Ipilimumab 50 mg and 200 mg) in India from local distributor?
It is always better to check the credential of the person / distributor before confirming.
As per the legal guidelines, only patients can import the product after getting proper documentation.
Patients must check following documents before importing Yervoy?
- How the product entered in India
- How is the packaging
- Courier / Shipping Details
- Verification of the foreign supplier e.g. drugs license and government approval of the ware house etc.
- Import documents
- Bill of entry of custom department
Please do not buy Yervoy where cash payment in involved
How long does yervoy take to work?
You’ll receive YERVOY as an infusion in your vein. Typically, you’ll get one dose every three weeks for up to 4 doses. It takes about 90 minutes to get a full dose. Your healthcare provider may change how often you receive YERVOY or how long the infusion may take.
Send your enquiry to find Yervoy (Ipilimumab) in UAE Iraq, Iran, Saudi Arabia, Jordan, Mexico, Argentina, Brazil, Chile, Colombia, Peru, Venezuela, Romania, Switzerland, Georgia, Turkey, Italy, UK, Ukraine, Azerbaijan, Latvia, Poland, Slovakia, Armenia, Kazakhstan, Moldova, Tajikistan, Turkmenistan, Uzbekistan, Mongolia, Algeria, Mauritius, Uganda, Zimbabwe. Australia and New Zealand. China, Cambodia, Indonesia, Malaysia, the Philippines, Singapore, Thailand, Vietnam, Hong Kong.
Are there any side-effects/ adverse reactions/precautions associated with treatment with Ipilimumab?
It is recommended to seek your doctor’s medical advice about side effects
How do I contact S S Healthcare?
You can reach us on Tollfree – +91 1800 889 1064 | 9310090915
Email: you can also sent enquiries directly to info@ikrispharmanetwork.com. We will respond within 24 hours after receiving your mail. Please mention detailed inquiry.
Conclusion: Ipilimumab is a first-in-class T-cell potentiator that has significant activity against stage IV melanoma. It has a significant improvement in the overall survival rate among patients with the metastatic melanoma, with the substantial long-term advantages observed among a subgroup of patients. However, adverse effects could be hazardous but can be manageable.
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