Padcev (Enfortumab Vedotin-ejfv)
- Name: PADCEV
- Generic Name: Enfortumab Vedotin-ejfv
- Dosage Form & Strength: Injection for IV infusion 20 mg & 30 mg vials
- Manufactured: Astellas Pharma US, Inc.
Medical Uses
Padcev (enfortumab vedotin-ejfv) is a Nectin-4-directed antibody and microtubule inhibitor conjugate used:
- As a single agent for the treatment of adults with locally advanced or metastatic urothelial cancer who have previously been treated with programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor and platinum-containing chemotherapy, or are ineligible for cisplatin-containing chemotherapy and have previously treated with one or more prior lines of therapy.
- Along with medicine pembrolizumab to treat adults with locally advanced or metastatic urothelial cancer (mUC) who are not eligible for cisplatin-containing chemotherapy.
The recommended dose of Padcev injection as a single agent is 1.25 mg/kg (up to a maximum of 125 mg for patients ≥100 kg) administered as an intravenous (IV) infusion over 30 minutes on Days 1, 8, and 15 of a 28-day cycle until disease progression or unacceptable toxicity.
When used in combination with pembrolizumab, the recommended dose of Padcev is 1.25 mg/kg (up to a maximum of 125 mg for patients ≥100 kg) administered as an intravenous (IV) infusion over 30 minutes on Days 1 and 8 of a 21-day cycle until disease progression or unacceptable toxicity.
Warning & Precautions
- Critical cutaneous side effects, including fatal cases of SJS or TEN, may occur in patients treated with Padcev injection. SJS and TEN may occur predominantly during the first cycle of treatment but may occur later. Monitor patients throughout treatment for skin reactions. Consider topical corticosteroids and antihistamines.
- Hyperglycemia and diabetic ketoacidosis (DKA), including fatal events, may occur in patients with and without preexisting diabetes mellitus, treated with this drug. Closely monitor blood glucose levels in those with, or at risk for, diabetes mellitus or hyperglycemia. In case the blood glucose is increased (>250 mg/dL), withhold therapy.
- Serious, life-threatening, or fatal pneumonitis/ILD may occur in patients treated with Enfortumab vedotin-ejfv. Monitor patients for symptoms of pneumonitis/ILD such as cough, hypoxia, dyspnea, or interstitial infiltrates on radiologic exams. Assess and exclude infectious, neoplastic, and other causes for such symptoms through relevant investigations.
- Peripheral neuropathy may occur in patients treated with Enfortumab vedotin-ejfv as a single agent. Monitor patients for symptoms of new or worsening peripheral neuropathy and interrupt or reduce the dose when peripheral neuropathy occurs. Permanently stop treatment in patients who develop Grade >3 peripheral neuropathy.
- Ocular disorders may occur in patients treated with Padcev as a single agent. Ensure adequate venous access before starting treatment and monitor for possible extravasation during administration. In case extravasation occurs, stop the infusion and monitor for side effects.
Documentation & Availability
What documents are required to import PADCEV to India?
\PADCEV (enfortumab vedotin-ejfv) injections can be imported by patients or government hospitals on the name of the patients only.
The following documentation is required to import the product:
- A valid prescription from a qualified doctor.
- Patient’s diagnostic reports.
- Patient’s ID proof (issued by the Government of India).
How is the order confirmed?
The order will be confirmed only after the receipt of:
- A valid prescription from a doctor.
- Import permit if applicable.
Is PADCEV available in India?
PADCEV (enfortumab vedotin-ejfv injection) is a (prescription drug, prescription medication, or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.
S S Healthcare (S S Healthcare) helps import cancer medicines on the named patient supply (NPS). Indian Pharma Network is the facilitator providing input
- Availability of Kineret (Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka).
- Kineret Available in India (Noida, Delhi, Mumbai, Gurgaon, Lucknow, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc
- Determining Medicine Price.
- Sourcing genuine and reliable sources from the USA, Canada, Europe, and Australia.
- Ensuring 100% transparency.
PADCEV can be made available to patients, doctors, and hospitals in Mumbai, Kolkata, Hyderabad, Goa, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow, and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and an import permit.
S S Healthcare (S S Healthcare) can facilitate the supply of PADCEV (prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable).
Please contact +91-7575883015 | Number: +91-7575883015 or write us at sshealthcare1012@gmail.com for Padcev 20 mg/30 mg price in India.
We take to guarantee quality and delivery anywhere in the world as per the buyer’s requirements.
Sourcing & Delivery
S S Healthcare is able to source the PADCEV (Cancer Treatment Medicines) from across the globe and has the ability to supply. S S Healthcare offers its customers worldwide access to the best available treatment.
S S Healthcare is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.
FAQ
What is the Generic Name for the trade name drug Padcev®?
Enfortumab vedotin-ejfv is a Generic Name for the trade name drug Padcev®.
What is the Manufacturer’s Name of Padcev®?
Padcev® is manufactured by Astellas Pharma US, Inc.
Is Padcev® approved by the FDA?
Yes, Padcev® is approved by the FDA. Date of first approval: December 18, 2019.
What is the dosage and form of Padcev® supplied?
Padcev® is supplied as injections: 20 mg and 30 mg of enfortumab vedotin-ejfv as a lyophilized powder in a single-dose vial for reconstitution for intravenous use.
How much does Padcev® cost in India?
The cost of Padcev in India can vary. To procure this therapeutic drug legally, you can call or WhatsApp +91-7575883015 or send mail to sshealthcare1012@gmail.com.
What are the storage conditions of Padcev®?
Store Padcev® vials refrigerated at 2°C to 8°C (36°F to 46°F) in the original carton. Avoid freezing and shaking the vials.
Is it safe to buy Padcev® online in India?
Yes, one can buy Padcev online in India at the lowest price from the S S Healthcare if this medicinal product is not (yet) registered or available in their country. We can help facilitate the supply of Padcev® through legal channels.
Where is padcev available in India?
Padcev available in India (Noida, Delhi, Mumbai, Gurgaon, Lucknow, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc
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