Pepaxto
- Medicine Name: Pepaxto
- Generic Name: Melphalan Flufenamide
- Dosage Form & Strength: Injection: 20 mg
- Manufactured By: Oncopeptides AB
Medical Uses
Pepaxto is an alkylating drug used together with dexamethasone, for the treatment of adult patients with relapsed/refractory multiple myeloma (RRMM) who have received at least 4 prior lines of therapy and whose cancer is refractory to at least one immunomodulatory agent, one proteasome inhibitor, and one CD38-directed monoclonal antibody.
Recommended Dosage: The recommended dosage of Pepaxto injection is 40 mg administered intravenously over 30 minutes on Day 1 of each 28-day cycle until the disease is progressive or until unacceptable toxicity. Administer dexamethasone 40 mg orally or intravenously on Days 1’st, 8’th, 15’th and 22’nd of each cycle. For patients aged 75 years or older, reduce the dose of dexamethasone to 20 mg.
Warning & Precautions
- Thrombocytopenia occurred in patients who received melphalan flufenamide along with dexamethasone. Platelets needs to be monitored during treatment, and more frequently during the initial 2 months of therapy. Do not use it in case the platelet count is below 50 x 109/L.
- Neutropenia occurred in patients who received injection pepaxto with dexamethasone. Monitor neutrophil counts during treatment. Monitor more frequently during the initial 2 months of treatment. Do not administer this drug if absolute neutrophil count is below 1 x 109/L.
- Anemia occurred in patients who received melflufen pepaxto with dexamethasone. Monitor red blood cell counts (RBCs) during treatment. Monitor more frequently during the initial 2 months of treatment. Dosage modification and dose delay may be required to allow for recovery of RBCs.
- Secondary malignancies such as acute leukemia or myelodysplastic syndromes have occurred in patients with multiple myeloma (MM) who have received this alkylating drug. Patients needs to be monitored for long-term for the development of secondary malignancies.
- Depending on its mechanism of action, Pepaxto 20mg INJECTION can cause fetal harm if used by a pregnant woman because it is genotoxic and targets actively dividing cells. Females of reproductive potential should use appropriate contraception during treatment and for 6 months after the final dose.
- Because of the potential for severe side effects in the breastfed child, respective women should not breastfeed during treatment with this medicinal product and for 7 days after the final dose.
Documentation & Availability
What documents are required to import PEPAXTO to India?
PEPAXTO (melphalan flufenamide) injection can be imported by patients or government hospitals on the name of the patients only.
The following documentation is required to import the product:
- A valid prescription from a qualified doctor.
- Patient’s diagnostic reports.
- Patient’s ID proof (issued by the Government of India).
How is the order confirmed?
The order will be confirmed only after the receipt of:
- A valid prescription from a doctor.
- Import permit if applicable.
Is PEPAXTO available in India?
PEPAXTO (melphalan flufenamide injection) is a (prescription drug, prescription medication or prescription medicine) pharmaceutical drug that legally requires a medical prescription to be dispensed.
S S Healthcare (S S Healthcare) helps import cancer medicines on the named patient supply (NPS). S S Healthcare is facilitator providing input
- On availability of Pepaxto in India (Ahmedabad, Mumbai, Kolkata, Hyderabad, Chennai, Delhi, Bangalore and Pune etc.)
- Medicine Price.
- Finding Genuine, Legitimate and Reliable source from USA, Canada, Europe, and Australia
- Ensuring 100% transparency.
PEPAXTO can be made available to patients, doctors and hospitals at Mumbai, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore, Srinagar, Jammu, Jaipur, Chandigarh, Ludhiana, Noida, Gurgaon, Lucknow and Pune and other cities in India. The order will be confirmed only after the receipt of a valid prescription from the doctor and import permit.
S S Healthcare (S S Healthcare) can facilitate the supply of PEPAXTO (prescription medicines) to all locations in the world and in India after fulfilling the legal requirement (if applicable)
Please contact +91-7575883015 | Toll-Free No: +91-7575883015 or write us at sshealthcare1012@gmail.com for Pepaxto price in India.
We take guarantee of quality and delivery anywhere in the world as per the buyer’s requirements.
Sourcing & Delivery
S S Healthcare is able to source the PEPAXTO (Cancer Treatment Medicines) from across the globe, and has the ability to supply. S S Healthcare offers its customers worldwide access to the best available treatment.
S S Healthcare is able to dispense any valid prescription in the shortest possible time. All prescriptions are dispensed and checked by registered pharmacists and dispatched to the Patient’s address only from New Delhi, India.
FAQ
What is the Generic Name for the trade name drug Pepaxto®?
Melphalan Flufenamide is Generic Name for the trade name drug Pepaxto®.
What is the Manufacturer Name of Pepaxto 20mg?
Pepaxto 20mg is manufactured by Oncopeptides AB.
Is Pepaxto® approved by the FDA?
Yes, Pepaxto® is approved by the FDA. Date of approval: On 26 February 2021.
What is Pepaxto®?
Pepaxto® is an anticancer peptide-drug conjugate used for use in combination with medicine dexamethasone to treat adult patients with relapsed or refractory multiple myeloma.
What is the dosage and form of Pepaxto® supplied?
Pepaxto® is supplied for injection: 20 mg melphalan flufenamide as a lyophilized powder in single-dose vial for reconstitution and dilution for intravenous use.
How is Pepaxto® taken?
Pepaxto® is taken at 40 mg dose, intravenously over 30 minutes on Day 1’st of each 28-day treatment cycle. It is taken together with drug dexamethasone.
What are the most common side effects due to Pepaxto®?
Most common side effects due to Pepaxto® include: nausea, fatigue, diarrhea, pyrexia and respiratory tract infection.
How much does Pepaxto® cost in India?
The Pepaxto cost in India is very reasonable. In order to procure this MM medication authentically, you can call or WhatsApp +91-7575883015 or send mail to sshealthcare1012@gmail.com.
What are the storage conditions of Pepaxto®?
Store refrigerated at 2 to 8°C (36 to 46°F) and protect from light. Retain the original carton until use.
Is it safe to buy Pepaxto® online?
Yes, In order to buy Pepaxto online in India, always look for an absolutely authentic, legitimate, WHO-GDP and ISO certified Pharmaceutical Wholesaler/Distributor/Supplier.
What are the Highlights of prescribing information for Pepaxto®?
Click Here to download full Pepaxto prescribing information.
Contact Patient Support
If you have any questions or need any help, contact our Patient Support Team. We will get in touch with you within 24 hours from Monday to Friday between 9:00 and 10:00 CET.
Email Address
Sshealthcare1012@gmail.com
+91 7575883015
Landline
079 48916267
Disclaimer
All Trademarks and Brands that appear on the website belong to their respective owners, and S S Healthcare does not lay any claim on them. We only provide information.
