Trodelvy (Sacituzumab govitecan-hziy)
- Medicine Name: Trodelvy
- Generic Name: Sacituzumab Govitecan-hziy
- Dosage Form & Strength: For injection: 200 mg , 180 mg lyophilized powder in a single-dose vial
- Manufactured By: Gilead Sciences, Inc.
Medical Uses
Trodelvy is a Trop-2-directed antibody and topoisomerase inhibitor conjugate used to treat adult patients with:
- metastatic triple-negative breast cancer (mTNBC) who have received at least 2 prior therapies for metastatic disease.
- locally advanced/metastatic urothelial cancer (mUC) who have previously treated with a platinum-containing chemotherapy and either programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor.
The recommended dose is 10 mg/kg weekly on Days 1 and 8 of each 21-day cycle, or until disease progression or unacceptable toxicity occurs. One should avoid substituting or combining Trodelvy with other irinotecan-containing medications. Administer only as an intravenous infusion, not as a bolus. Pre-infusion medicine and close monitoring are recommended, as well as necessary treatment changes to manage side effects.
Warning & Precautions
- Sacituzumab Govitecan-hziy can cause severe or life-threatening neutropenia. Withhold it for absolute neutrophil count below 1500/mm3 on Day 1’st of any cycle or neutrophil count below 1000/mm3 on Day 8’th of any cycle. Withhold it for neutropenic fever.
- Trodelvy breast cancer drug can cause severe diarrhea. Withhold it for Grade 3-4 diarrhea at the juncture of scheduled treatment administration and resume when resolved to ≤ Grade 1.
- Sacituzumab Govitecan-hziy can cause severe and life-threatening hypersensitivity. Pre-infusion drug for patients receiving sacituzumab govitecan hziy is recommended. Observe patients precisely for infusion-related reactions during each infusion and for at least 30 minutes following completion of each infusion.
- Patients who are homozygous for the uridine diphosphate-glucuronosyl transferase 1A1 (UGT1A1)*28 allele are at greater risk for neutropenia and may be at greater risk for other adverse reactions following starting of trodelvy 180 mg treatment.
- Precisely assess patients with reduced UGT1A1 activity for the severe neutropenia. The apt dose for patients who are homozygous for UGT1A1*28 is not specified and should be considered based on the tolerance to treatment.
- Mechanism of action suggest that the trodelvy therapy can be responsible for causing teratogenicity and/or embryo-fetal lethality in case administered to a pregnant woman.
Documentation & Availability
What documents are required to import Trodelvy?
Trodelvy (Sacituzumab govitecan-hziy) injection can be imported by patients or government hospitals on behalf of patients.
The following documentation are needed to import the product:
- A valid prescription from a qualified doctor.
- Patient’s diagnostic reports.
- Patient’s ID proof (issued by the Government of the respective country).
How is the order confirmed?
The order will be confirmed only after the receipt of:
- A valid prescription from a doctor.
- Import permit if applicable.
Is Trodelvy available worldwide?
Trodelvy (Sacituzumab govitecan-hziy) injection is a prescription pharmaceutical drug that legally requires a medical prescription for dispensation.
S S Healthcare facilitates the import of critical medications like Trodelvy globally, ensuring the named patient supply (NPS). S S Healthcare is the facilitator that provides essential support for:
- Availability of Trodelvy (Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka).
- Trodelvy available in India (Noida, Delhi, Mumbai, Gurgaon, Lucknow, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc
- Determining Medicine Price.
- Sourcing genuine and reliable sources from the USA, Canada, Europe, and Australia.
- Ensuring 100% transparency.
Trodelvy can be made available to patients, doctors, and hospitals in various countries across the globe. The order will be confirmed only after receiving a valid prescription from the doctor and, if required, an import permit.
S S Healthcare can facilitate the supply of Trodelvy (prescription medicine) to locations worldwide while adhering to legal requirements (if applicable).
We assure quality and worldwide delivery as per the buyer’s specifications.
Sourcing & Delivery
S S Healthcare is proficient in sourcing Trodelvy from around the world and has the capability to supply it. We offer global access to the best available treatment for our customers worldwide in countries like Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka.
S S Healthcare is committed to dispensing any valid prescription promptly. All prescriptions are dispensed and verified by registered pharmacists and are dispatched only to the patient’s address. Your health and well-being are our top priorities
FAQ
What is the Generic Name for the trade name drug Trodelvy®?
Sacituzumab Govitecan-hziy is Generic Name for the trade name drug Trodelvy®.
Is Trodelvy® approved by the FDA?
Yes, Trodelvy® is approved by the FDA. Date of approval: April 22, 2020.
What is Trodelvy®?
Trodelvy is a kind of medicine named an antibody-drug conjugate (ADC). Unlike other existing traditional chemotherapy, antibody-drug conjugate contains 3 parts: an antibody, an anti-cancer medicine, and a linker.
What is the dosage and form of Trodelvy® supplied?
Trodelvy® is supplied for injection: 180 mg off-white to yellowish lyophilized powder in a single-dose vial.
What are the most common side effects due to Trodelvy®?
Most common side effects due to Trodelvy® include: nausea, diarrhea, fatigue, neutropenia, anemia, vomiting, alopecia, decreased appetite, constipation, rash, and abdominal pain.
How much does Trodelvy® cost in India?
The trodelvy cost in India is reasonably economical. In order to procure this mTNBC medicine authentically, you can call or WhatsApp +91-7575883015 or send mail to sshealthcare1012@gmail.com.
What are the storage conditions of Trodelvy®?
Store vials of Trodelvy in a refrigerator at 2°C to 8°C (36°F to 46°F) in the original carton in order to protect from the light until time of reconstitution. Do not freeze.
How long is treatment with Trodelvy?
Trodelvy is a type of treatment called an antibody-drug conjugate (ADC) that is designed to work differently than traditional chemotherapy.
Is Trodelvy a chemo?
Trodelvy is a type of treatment called an antibody-drug conjugate (ADC) that is designed to work differently than traditional chemotherapy.
How many cycles of Trodelvy ?
The recommended dosage of Trodelvy is 10 mg/kg administered as an intravenous infusion once weekly on Days 1 and 8 of 21-day treatment cycles. Continue treatment until disease progression or unacceptable toxicity.
Who is eligible for Trodelvy ?
Trodelvy is a prescription medicine used to treat adults with triple-negative breast cancer (negative for estrogen and progesterone hormone receptors and HER2) that has spread to other parts of the body or cannot be removed by surgery, and who have received two or more prior treatments, including at least one treatment
What is the success rate of Sacituzumab?
In clinical trials, sacituzumab govitecan has demonstrated high efficacy. In the IMMU-132 trial, the ORR was found to be 33.3% including complete response in three patients. The clinical benefit rate, including stable disease for >6 months was 45.4%
Is trodelvy available in Asia?
Trodelvy injection is available in Asian countries like Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka.
How can I get Trodelvy injection?
S S Healthcare can facilitate the supply of Trodelvy (prescription medicine) to locations worldwide while adhering to legal requirements.
Will I lose my hair on Trodelvy ?
Sacituzumab govitecan may cause hair loss. Any hair loss caused should be temporary and in most cases your hair will begin to grow back once your treatment has ended.
Where is Trodelvy available in India?
Trodelvy available in India (Noida, Delhi, Mumbai, Gurgaon, Lucknow, Kolkata, Hyderabad, Chennai, Ahmedabad, Delhi, Bangalore and Pune etc
Contact Patient Support
If you have any questions or need any help, contact our Patient Support Team. We will get in touch with you within 24 hours from Monday to Friday between 9:00 and 10:00 CET.
Email Address
Sshealthcare1012@gmail.com
+91 7575883015
Landline
079 48916267
Disclaimer
All Trademarks and Brands that appear on the website belong to their respective owners, and S S Healthcare does not lay any claim on them. We only provide information.
